Synthetic biology enables scientists to design new sequences of DNA from scratch to engineer novel biological functions and systems within microorganisms. Identifying genetically engineered microorganisms can be challenging due to their scarcity in the larger population. The small size of these microorganisms can make isolating them even more challenging.
Microorganisms are transfected with the desired genetic information along with a fluorescent reporter gene, such as GFP. Individual GFP-positive cells are then identified and dispensed with Namocell’s Single Cell Dispenser, then cultured for downstream characterization.
- Process 1 billion bacterial cells per hour
- Isolate microbes as small as 0.4 µm in diameter
- High cell recovery
- No sample loss
- Quick setup in under 3 min
- No cross-contamination
- No maintenance
Namocell Single Cell Dispensers are highly efficient and consistent at dispensing single cells, with dispensing efficiency (percentage of dispensed wells with single cells) of 80-90% for CHO cells compared to ~30% using manual pipetting.